Abstract

Different analytic expressions for the membrane potential distribution of membranes subject to synaptic noise have been proposed, and can be very helpful to analyze experimental data. However, all of these expressions are either approximations or limit cases, and it is not clear how they compare, and which expression should be used in a given situation. In this note, we provide a comparison of the different approximations available, with an aim to delineate which expression is most suitable for analyzing experimental data.

Complementary Information and Material

NEURON program to simulate the model and compare it to various analytic expressions: ZIP (536 kByte)

PDF with several supplementary figures which compare the Vm distributions obtained from numerical simulations with different analytic expressions for various parameter sets: PDF (51 kByte)